Search results for "ISM [radio lines]"
showing 10 items of 1018 documents
Homeomorphisms of finite distortion : from the unit ball to cusp domains in R^{3}
2016
Galantamine is an allosterically potentiating ligand of the human α4/β2 nAChR
2000
Galantamine (ReminyI ) is a novel drug treatment for mild to moderate Alzheimer's disease (AD). Originally established as a reversible inhibitor of the acetylcholine-degrading enzyme acetylcholinesterase (AChE), galantamine also acts as an allosterically potentiating ligand (APL) on nicotinic acetylcholine receptors (nAChR). Having previously established this second mode of action on nAChRs from murine brain, we demonstrate here the same action of galantamine on the most abundant nAChR in the human brain, the α4/β2 subtype. This nAChR-sensitizing action is not a common property of all, or most, AChE inhibitors, as is shown by the absence of this effect for other therapeutically applied AChE…
Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.
2022
This study was aimed to analyze the commonalities and distinctions of voltage-gated sodium channels, Nav1.2, Nav1.6, in neurodevelopmental disorders. An observational study was performed including two patients with neurodevelopmental disorders. The demographic, electroclinical, genetic, and neuropsychological characteristics were analyzed and compared with each other and then with the subjects carrying the same genetic variants reported in the literature. The clinical features of one of them argued for autism spectrum disorder and developmental delay, the other for intellectual disability, diagnoses confirmed by the neuropsychological assessment. The first patient was a carrier of SCN2A (p.…
Serotypes, Antibiotic Resistance, and Class 1 Integrons in Salmonella Isolates from Pediatric Cases of Enteritis in Tehran, Iran
2011
The present study was conducted to investigate serotype distribution, antimicrobial resistance patterns, carriage of class 1 integron, and clonality of Salmonella strains isolated from patients aged 0-12 years in Tehran, Iran, during 2007-2008. A total of 139 Salmonella isolates were studied. Salmonella serotypes Enteritidis, Infantis, and Typhimurium included 84.9% of isolates, Enteritidis accounting for 41.7%. The most prevalent resistances were to doxycycline (64.7%), nalidixic acid (61.2%), tetracycline (51.8%), and streptomycin (42.8%). Fifty-three (38.1%) isolates contained class 1 integron. Eight different gene cassettes were identified, aadA1 being the most frequently encountered. P…
Antropologia filosòfica i literatura (II): TH. W. Adorno i S. Cavell interpreten Fi de partida de S. Beckett
2006
Abstract: This paper is a philosophical reading of Samuel Beckettʼs Endgame, taking into account many of the critic suggestions of Adornoʼs interpretation, from his negative dialectics in the note Versuch, das Endspiel zu verstehen. It deals as well with the acute comments by Stanley Cavell in the chapter V of his book "Must We Mean What We Say?", a view from the philosophy of the ordinary language on this play of the Irish writer. In doing so this paper tries to commemorate the centenary of Beckettʼs birth and claims for the necessary study of the relationships between philosophical anthropology and literature in our present.
Inchieste sociali e subalternità. Dal concetto gramsciano di "subalterno" alle storie di vita di Scotellaro e Montaldi. Rappresentazione e intervento…
2014
Seasonal pattern and amplitude: a logical framework to analyse seasonality in tourism. An application to bed occupancy in Sicilian hotels
2011
Many studies have investigated seasonality in tourism in terms of its causes and impacts, from both theoretical and applied perspectives. However, the definition of seasonality and, most of all, its application and measurement have not received the same degree of attention. In recognizing that seasonality has two main facets – pattern and amplitude – this paper critically examines the main seasonality measures proposed in the tourism literature, classifying them according to their properties and their most appropriate use. The framework then proposed is used to analyse a standard and comparable efficiency measure, such as the bed occupancy rate of Sicilian accommodation establishments, pla…
The Transition to Upper Secondary Level After Basic Education for Adolescents with Autism Spectrum Disorder in Finland
2019
This chapter provides an exploration of the preparation of pupils with autism spectrum disorder (ASD) for transition to upper secondary level after Finnish basic education. It also examines the importance of supports required during the transition phase. Two examples of pupils with ASD (Kalle and Maija) are utilized to illustrate how to plan and support pupils with ASD during their initial post-school transition. Transitions are defined, after which education opportunities after basic education for pupils with ASD in Finland are examined. This is followed by a brief illustration of the Finnish comprehensive school system to provide context with a focus on support arrangements and the prepar…
Food selectivity in autism spectrum disorders: a systematic review.
2013
Autism spectrum disorders are characterized by difficulties with reciprocal social interactions and restricted patterns of behavior and interest; one of these characteristic behaviors is food selectivity. The objective of this study was to perform a systematic review of the literature published between 1970 and 2013 concerning this eating behavior. The articles identified were analyzed in terms of sample size, study design, and criteria for assessment and intervention, as well as the results, level of evidence and grade of recommendation. The main search was conducted in Medline, Cochrane Library, Scielo, ScienceDirect, and Embase). There is empirical evidence and an overall scientific con…
Sense of Belonging and Life Transitions for Two Females with Autism Spectrum Disorder in Finland
2015
AbstractSense of belonging refers to the degree to which individuals feel included, accepted, and supported by others in a variety of social settings. This study, based on the narratives of two females (ages 26 and 29) with Autism Spectrum Disorder (ASD), examines sense of belonging and various life transition issues that may appear throughout childhood, adolescence, and adulthood in the absence of appropriate social supports. Hearing the voices of females with autism is important, because the number of girls diagnosed with ASD has grown. Women on the spectrum can potentially provide significant insights into the services required to feel a sense of belonging to society. Qualitative analysi…